A Review of Multi-Threat Medical Countermeasures against Chemical Warfare and Terrorism From: Military Medicine | Date: November 1, 2004| Author: Broomfield, Clarence A; Smith, William J; Stojiljkovic, Milos P; Cowan, Fred M | Copyright Association of Military Surgeons of the United States Nov 2004. Provided by ProQuest LLC.Copyright information

The Multi-Threat Medical Countermeasure (MTMC) hypothesis has been proposed with the aim of developing a single countermeasure drug with efficacy against different pathologies caused by multiple classes of chemical warfare agents. Although sites and mechanisms of action and the pathologies caused by different chemical insults vary, common biochemical signaling pathways, molecular mediators, and cellular processes provide targets for MTMC drugs. This article will review the MTMC hypothesis for...

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