Abnormal QT Prolongation and Psychotropic Drug Therapy in Psychiatric Patients: Significance of Bradycardia-dependent QT Prolongation

From: Journal of Electrocardiology | Date: October 1, 2004| Author: Fujishima, Masatoshi; Sadanaga, Fumiko; Yao, Hiroshi; Sadanaga, Tsuneaki | Copyright information

Abstract: Because many psychotropic drugs have electrophysiological properties similar to antiarrhythmic drugs, they might lengthen QT interval and cause torsades de pointes. Electrocardiograms were obtained in 688 psychiatric patients receiving psychotropic drugs. A QTc interval >460 ms was observed in 96 (14%) patients. To elucidate the heart rate dependence of QT prolongation, we measured QT intervals and the preceding R-R intervals at various heart rates by 24-hour Holier electrocardio...

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Abnormal QT Prolongation and Psychotropic Drug Therapy in Psychiatric Patients: Significance of Bradycardia-dependent QT Prolongation
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