refractive

RENO, NV-Methotrexate is an effective treatment to improve the changes in vision and irregular astigmatism associated with diffuse lamellar keratitis (DLK), said Kurt A. Buzard, MD.

Dr. Buzard reported using methotrexate to manage DLK (the "SOS syndrome") in 13 eyes of seven patients. In all cases, vision was good in the early postop period, he said.

However, within 2 to 4 weeks, the patients experienced reductions in both uncorrected and best corrected visual acuities with variable refractions and irregular astigmatism. All patients were treated with methotrexate 10 mg once ...

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