Hamsters predisposed to sucrose-induced cholesterol gallstones (LPN strain) are more resistant to excess dietayr cholesterol than hamsters that are not sensitive to...

The Journal of Nutrition | June 1, 2001| | Copyright

Hamsters Predisposed to Sucrose-Induced Cholesterol Gallstones (LPN Strain) Are More Resistant to Excess Dietary Cholesterol than Hamsters That Are Not Sensitive to Cholelithiasis Induction1

ABSTRACT We compared the effects of cholesterol feeding in male hamsters from two strains with different propensities to sucrose-induced cholelithiasis; Laboratoire de Physiologie de la Nutrition (LPN) hamsters are predisposed to developing biliary cholesterol gallstones, whereas Janvier (JAN) hamsters are not. When fed a basal control diet, LPN hamsters had a lower cholesterolemia (-21 %, P = 0.01) than ...

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