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ELEVATED EXPRESSION OF CYCLOOXYGENASE-2 IN ADENOCARCINOMA OF THE PAROTID GLAND: INSIGHTS INTO MALIGNANT TRANSFORMATION OF PLEOMORPHIC ADENOMA
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Pleomorphic adenoma, the most common type of tumor of the parotid gland, may transform into a malignant tumor. In the current study, we investigated whether the expression of cyclooxygenase-2 (COX-2) is elevated in adenocarcinoma as compared to pleomorphic adenoma. Ten pleomorphic adenomas and 10 adenocarcinomas were examined. The tumor specimens were immunohistochemically stained with antibodies against COX-2 and Ki-67. The labeling indices of COX-2 in pleomorphic adenoma and adenocarcinoma ...
Related newspaper, magazine, and journal articles from HighBeam Research
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Imaging case study of the month: Magnetic resonance sialography
The Annals of Otology, Rhinology & Laryngology
; INTRODUCTION In patients with swelling and painful conditions of the salivary glands, a large range of diagnostic imaging modalities is available. X-ray sialography is performed to demonstrate changes in the duct configuration or caliber. Since the first description of X-ray sialography in the
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Pleomorphic adenoma of the parotid.
American Family Physician
; Pleomorphic adenomas are the most common type of salivary gland tumor. Consequently, primary care physicians need to know how to diagnose and manage these lesions, which most often occur in the parotid gland. Appropriate management is crucial: these tumors can be cured if they are correctly
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Carcinosarcoma of the parotid gland: Report of a case with cytohistologic and immunohistochemical findings
Archives of Pathology & Laboratory Medicine
; * True malignant mixed tumors (carcinosarcomas) of salivary gland origin are exceedingly rare and demonstrate malignant epithelial and stromal components. We report a case of parotid gland carcinosarcoma that showed squamous cell carcinoma and malignant fibrous hystiocytoma without clinical or
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Carcinosarcoma of the Parotid Gland: Report of a Case With Immunohistochemical Findings
The Annals of Otology, Rhinology & Laryngology
; Objectives: Carcinosarcoma (true malignant mixed tumor) of the parotid gland is an extremely uncommon tumor composed of both carcinomatous and sarcomatous components. An understanding of this manifestation is crucial to guide management and treatment of this disease. Methods: A patient who
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Scalp and intracranial metastasis from pleomorphic adenocarcinoma of the parotid gland
Neurology India
; Sir, Adenocarcinoma of the salivary gland is an aggressive tumor with the tendency to metastasize locally or through lymphatics. Intracranial metastasis through hematogenous route from salivary gland malignant tumor is uncommon and most of the reported cases are from the adenocystic carcinoma of
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Recurrent pleomorphic adenoma of the parotid gland involving the osseous external auditory canal: With a note on the foramen of Huschke
The Annals of Otology, Rhinology & Laryngology
; A recurrence of a parotid pleomorphic adenoma presenting as an external ear canal mass is reported. The route of extension was radiographically documented as an incompletely closed foramen of Huschke. The historical and developmental features of this foramen and the mechanisms of tumor extension as
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Familial occurrence of acinic cell carcinoma of the parotid gland
Archives of Pathology & Laboratory Medicine
; We report the familial occurrence of acinic cell carcinoma involving the parotid gland, the first such report of which we are aware. The familial occurrence of any salivary gland neoplasm is rare. Several reports are present in the literature, including pleomorphic adenoma, Warthin tumor, carcinoma
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PLEOMORPHIC ADENOMA OF THE NASAL SEPTUM
The Annals of Otology, Rhinology & Laryngology
; Pleomorphic adenoma may occur in any site in which there is salivary gland tissue. It has rarely been described arising in the nasal cavity. We report a case of septal pleomorphic adenoma and discuss the clinical presentation and surgical management. KEY WORDS - pleomorphic adenoma, septum. CASE
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Value of technetium-99m pertechnetate imaging in the differential diagnosis of salivary gland lesions
The Annals of Otology, Rhinology & Laryngology
; INTRODUCTION A neoplasm of the parotid gland arises as a "cold" area on a salivary gland scintigram, whatever the nature of the neoplasm, with the exception of a Warthin' s tumor (papillary cystadenoma lymphomatosum) and some forms of oxyphilic adenomas. These latter tumors show increased uptake of
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Primary pulmonary pleomorphic adenoma: An immunohistochemical study and review of the literature
Archives of Pathology & Laboratory Medicine
; * Primary pleomorphic adenoma of the lung is an uncommon condition. We present a case of primary pulmonary pleomorphic adenoma and its immunohistologic features. The presence of immunoreactivity to both anticytokeratin and antivimentin antibodies for its epithelial components is suggestive of a
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