New Materials for Strongly Binding and Controllably Releasing Nucleic Acids

From: Clinical Chemistry | Date: November 1, 2004| Author: | Copyright information

1

New Materials for Strongly Binding and Controllably Releasing Nucleic Acids. H. Akhavan-Tafti, R. DeSilva, W.G. Cripps, R.A. Eickholt, R.S. Handley, K.S. Lauwers, M.D. Sandison, S. Siripurapu, and A.P. Schaap. Lumigen Inc., Southfield, MI

A new type of solid phase material for binding and releasing nucleic acids has been developed. The materials bind DNA and RNA with a strength far exceeding conventional materials and feature a novel mechanism to release bound nucleic acids. Unlike silica particle based materials and ion exchange polymeric resins, both of which elute bound nucleic acid ...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

Nucleic Acids Manufacturers Prepare to Fuel the Genomic Revolution.(Brief Article)
; ...opportunities for the nucleic acids industry, which plays...information. Suppliers of nucleic acids and oligonucleotides...of life increases. Nucleic acids are used widely in...mature segment, while nucleic acids for use in genetic...In drug discovery, nucleic ...
High-Volume Extraction of Nucleic Acids by Magnetic Bead Technology for Ultrasensitive Detection of Bacteria in Blood Components
; Background: Nucleic acid isolation, the...covered with nucleic acid-binding matrices...of bacterial nucleic acids from platelet...system and locked nucleic acid technology. Coamplification...either due to nucleic acid contamination...High-volume ...
Locking down locked nucleic acids
; ...class of nucleic acid analogs called locked nucleic acids (LNAT(TM...for native nucleic acids, and enhanced...incorporated into a nucleic acid adds 3-8...for other nucleic acids, and nuclease...the native nucleic acid is less stable...
* Nucleic Acid Deal.(Qiagen acquires Sawady Group)(Brief Article)
; Nucleic acid producer Qiagen (Venlo...second-largest supplier of nucleic acids to the Japanese market...leading global producer of nucleic acids, which are used as a raw...number-one producer of nucleic acids in Japan, the world's...
Ion-Mediated Nucleic Acid Helix-Helix Interactions
; ...for the folding of nucleic acids. We use the tightly...the ions bound to the nucleic acids, to investigate the...landscape for two parallel nucleic acid helices in the solution...simulations. INTRODUCTION Nucleic acids (DNAs and RNAs) are...molecules. The folding of ...
High-Throughput Purification of Viral RNA Based on Novel Aqueous Chemistry for Nucleic Acid Isolation
; ...extraction of viral nucleic acids from plasma samples...magnetic silica beads. Nucleic acids were bound to the...superior sensitivity of nucleic acid amplification technique...detection steps of NAT, nucleic acid isolation remains...of adsorption of nucleic ...
Peptide Nucleic Acid-Based In Situ Hybridization Assay for Detection of Parvovirus B19 Nucleic Acids
; Background: Peptide nucleic acid (PNA) molecules...complementary nucleic acid sequences with...detection of nucleic acids by in situ hybridization...consisting of peptide nucleic acid (PNA), a synthetic...detection of viral nucleic acids in clinical ...
Nucleic acid biosensor technology in clinical diagnosis, pathogen detection and drug discovery.
; ...novel silanes to immobilize nucleic adds for biosensor research...in antisense-type therapy or nucleic acid-small molecule interactions...hybrid with its complementary nucleic acid, where the formation of the...large numbers of molecules to nucleic acid sequences. As for the ...
Separation of Nucleic Acid Sequences.(Nanogen Inc.)(Brief Article)
; ...amplification and separation of nucleic acid sequences on a bioelectronic...asymmetrically amplifying nucleic acids to enhance detection of amplified...amplifying and analyzing nucleic acids using novel strand displacement...different samples containing nucleic acids of ...
Nucleic Acid Testing Using Surface Plasmon Resonance Fluorescence Detection
; ...accelerate the demand for nucleic acid diagnostics, one of...specific technologies for nucleic acid detection are needed...Application, of SPRF for nucleic acid testing involves immobilization...1). Biotin-tagged nucleic acid amplicons are hybridized...from the ...