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Fine Mapping of Milk Production QTL on BTA6 by Combined Linkage and Linkage Disequilibrium Analysis
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ABSTRACT
Combined linkage and linkage disequilibrium analysis were used to refine the position of a previously detected QTL affecting milk production traits on bovine chromosome 6. Through a series of single- and multitrait and single- and multipoint QTL analyses, the QTL could be positioned to a 7.5-cM interval surrounded by the markers BMS2508 and FBN12. The most significant results were found for fat percentage and protein percentage. This effect seemed to be caused by a QTL allele embedded in one specific marker haplotype that caused a reduction in fat and protein yields and a concomitant ...
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Linkage Disequilibrium Under Skewed Offspring Distribution Among Individuals in a Population
; ...reproduction events. Since a prediction of linkage disequilibrium can be written in terms of correlations...follows that the prediction of linkage disequilibrium is a function not only of the rate...the reproduction parameters. Low linkage disequilibrium is predicted if the offspring ...
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Nucleotide Polymorphism and Linkage Disequilibrium Within and Among Natural Populations of European Aspen (Populus tremula L., Salicaceae)
; ...of nucleotide polymorphisms and linkage disequilibrium have never been investigated in...averaged 0.016 across the five genes. Linkage disequilibrium was generally low, extending only...nucleotide polymorphism and low linkage disequilibrium suggest that it may be possible...
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Genetic Diversity and Background Linkage Disequilibrium in the North American Holstein Cattle Population
; ...the extent of background linkage disequilibrium (BLD) and disease trait associated linkage disequilibrium (DLD) in the US Holstein...expected, there is extensive linkage disequilibrium (LD) in the US Holstein population...
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Genetic Diversity and Linkage Disequilibrium in the Polynesian Population of Niue Island
; ...genetic diversity and high levels of linkage disequilibrium and should be ideal for mapping...78 0.02, p = 0.04). The higher linkage disequilibrium (d^sup 2^) between these loci in...genetic diversity and high levels of linkage disequilibrium that are consistent with the influence...
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Modeling Linkage Disequilibrium in Natural Populations: The Example of the Soay Sheep Population of St. Kilda, Scotland
; ABSTRACT The use of linkage disequilibrium to localize the genes...the investigation of linkage disequilibrium structures of several...efforts. However, the linkage disequilibrium structure of free-living...
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Accuracy of Genomic Selection Using Different Methods to Define Haplotypes
; ...some loci are in linkage disequilibrium (LD) with QTL alleles...combinations of marker alleles, and the relationship...directly for the marker alleles (Xu 2003). A second...more surrounding marker alleles and derive identical-by-des...
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HLA polymorphism and evaluation of European, African, and Amerindian contribution to the white and mulatto populations from Parana, Brazil
; ...haplotype frequencies, together with linkage disequilibrium patterns, are reported for 2 populations...POLYMORPHISM, ADMIXTURE, BRAZIL, LINKAGE DISEQUILIBRIUM The HLA system comprises a set...high degree of polymorphism, and linkage disequilibrium between alleles of the closely...
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Linkage Disequilibrium and Recent Selection at Three Immunity Receptor Loci in Drosophila simulans
; ...directional selection is an increase in linkage disequilibrium among the polymorphic sites that...polymorphic sites are in nearly perfect linkage disequilibrium, an unusual finding even with respect...recent past. The extent to which the linkage disequilibrium extends to the flanks ...
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Temporal Dynamics and Linkage Disequilibrium in Natural Caenorhabditis elegans Populations
; ...genetically stable populations, linkage disequilibrium between different chromosomes can...dynamics, and the maintenance of linkage disequilibrium despite a low yet significant level...was estimated from studies of linkage disequilibrium, either within local populations...
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Nucleotide Polymorphism and Linkage Disequilibrium in Wild Populations of the Partial Selfer Caenorhabditis elegans
; ...occur at all geographic scales. Linkage disequilibrium is extensive in the C. elegans...with the data is inferred from linkage disequilibrium, using "scattered" samples representing...to low polymorphism, extensive linkage disequilibrium, and high population subdivision...
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