Nucleic Acid Testing Using Surface Plasmon Resonance Fluorescence Detection

From: Clinical Chemistry | Date: October 1, 2004| Author: Kiaei, David; Lei, Jason; Shami, Saà Sustarsic, Dennis; ¯ Campbell, Bruce; d El | Copyright information

The completion of the Human Genome Project (1) is likely to accelerate the demand for nucleic acid diagnostics, one of the fastest growing segments of in vitro diagnostics. To meet this demand, fully automated, sensitive, and specific technologies for nucleic acid detection are needed.

Surface plasmon resonance fluorescence (SPRF) is an optical detection technology that offers kinetic analysis of biomolecular interactions in real time (2). SPRF technology uses a sensor composed of a di...

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