Quantitative, Rapid Europium(III) Nanoparticle-Label-Based All-in-One Dry-Reagent Immunoassay for Thyroid-Stimulating Hormone

From: Clinical Chemistry | Date: October 1, 2004| Author: Hà Jaakohuhta, Sinikka; Là Pelkkikangas, Anne-Maria; ¤ ¤ ¶ , Harri; Huhtinen, Petri; rmà vgren, Timo | Copyright information

Long-lifetime fluorescent europium(III) chelate nanoparticles have been shown to be applicable as labels in various heterogeneous and homogeneous immunoassays. Assay performance can be improved when these intrinsically labeled nanoparticles are used in combination with time-resolved fluorescence detection. In several previous publications, we have shown the potential of nanoparticle labels in different assay applications. In heterogeneous assays, the dynamic range of assays at low concentrati...

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