Localization and Imaging of Nucleic Acids on Nanoporous Aluminum Oxide Membranes

From: Clinical Chemistry | Date: October 1, 2004| Author: Durtschi, Jacob D; Smith, Roger E; Voelkerding, Karl V; Erali, Maria | Copyright information

The technologies currently available for nucleic acid analysis in the clinical laboratory rely on target amplification methods, such as PCR or transcription-mediated amplification, or signal amplification methods, such as branched-chain DNA, hybrid capture, Invader technology, and fluorescent, in situ hybridization. In current nucleic acid analyses, a multistep process consisting of sample preparation and purification followed by amplification and detection is required. A comprehensive method...

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