L-Selectin and Chemotaxis Throughout Bone Marrow Granulocyte Maturation in the Bovine From: Journal of Dairy Science | Date: October 1, 2004| Author: Monfardini, E; Van Merris, V; Paape, M; Duchateau, L; Burvenich, C | Copyright American Dairy Science Association Oct 2004. Provided by ProQuest LLC.Copyright information

ABSTRACT

Polymorphonuclear neutrophilic leukocytes (PMNL) play a pivotal role during inflammation. Bone marrow (BM) reserves are depleted as cells are released into circulation for recruitment to infection sites. Expression of L-selectin on the cell membrane allows neutrophils to roll along the activated endothelium. Whereas mechanisms leading to recruitment to infection sites are well established, expression of BM adhesion molecules in cows is limited. In this study, we assess...