Superiority of 3-Dimensional Stereotactic Surface Projection Analysis over Visual Inspection in Discrimination of Patients with Very Early Alzheimer's Disease from Controls Using Brain Perfusion SPECT

From: The Journal of Nuclear Medicine | Date: September 1, 2004| Author: Asada, Takashi; Et al; Matsuda, Hiroshi; Ohnishi, Takashi; Imabayashi, Etsuko | Copyright information

In Alzheimer's disease (AD), regional cerebral blood flow (rCBF) in the posterior cingulate gyri and precunei has been reported to decrease even at a very early stage. It may be helpful to use statistical image analysis to distinguish slight decreases in rCBF in this area. We compared a 3-dimensional stereotactic surface projection (3D-SSP) technique with visual inspection in the discrimination of patients with very early AD from age-matched controls using brain perfusion SPECT. Methods: SPEC...

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