Non-pharmacologic cause of anti-emetic resistant postoperative nausea and vomiting

Anaesthesia and Intensive Care | February 1, 2001| | Copyright

A 38-year-old woman underwent thoracoscopy for talc pleurodesis for recurrent pneumothoraces. She had a history of frequent migraines treated with pethidine. Postoperatively the Anaesthetic Pain Registrar was rung because of continued nausea and vomiting thought to be associated with the pethidine infusion. This was unresolved despite metoclopramide and ondansetron. The patient was adamant that the infusion not be stopped nor that the opiate be altered although she did want the antiemetic altered to prochlorperazine. After consideration it was decided to add promethazine and administer a dose ...

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