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Classifying Asthma Severity in Children: Mismatch Between Symptoms, Medication Use, and Lung Function
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Current guidelines for asthma care categorize asthma severity based on the frequency of asthma symptoms, medication use, and lung function measures. The objective of this study was to determine whether lung function measures are consistent with levels of asthma severity as defined by the National Asthma Education and Prevention Program/Expert Panel Report 2 Guidelines. Parents of children aged 5-18 years with asthma seen in two outpatient subspecialty clinics completed questionnaires regardin...
Related newspaper, magazine, and journal articles from HighBeam Research
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Pharmacogenetic Differences in Response to Albuterol between Puerto Ricans and Mexicans with Asthma
American Journal of Respiratory and Critical Care Medicine
; Background: In the United States, Puerto Ricans and Mexicans have the highest and lowest asthma prevalence, morbidity, and mortality, respectively. Ethnic-specific differences in the response to drug treatment may contribute to differences in disease outcomes. Genetic variants at the β^sub
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ELECTROPHILIC HALOGENATION OF nido-5,6-C^sub 2^B^sub 8^H^sub 12^
Collection of Czechoslovak Chemical Communications
; Room-temperature chlorination of the dicarbaborane nido-5,6-C^sub 2^B^sub 8^H^sub 12^ (1) with CCl^sub 4^ in the presence of anhydrous AlCl^sub 3^ yielded a mixture of 7-Cl-5,6-C^sub 2^B^sub 8^H^sub 11^ (7-Cl-1) (yield 34 4-Cl-5,6-C^sub 2^B^sub 8^H^sub 11^ (4-Cl-1) (yield 20 3-Cl-5,6-C^sub 2^B^sub
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Is Forced Expiratory Volume in One Second the Best Measure of Severity in Childhood Asthma?
American Journal of Respiratory and Critical Care Medicine
; This essay focuses on whether FEV^sub 1^ is the best measure of asthma severity in childhood asthma. For better or worse, FEV^sub 1^ has become the gold standard lung function measurement in asthma, as it can be easily and quickly measured with relatively simple equipment. The current asthma
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POLYHEDRAL MONOCARBABORANE CHEMISTRY. FUNCTIONALITY AND ISOMERISM: REACTIONS OF THE [6-Ph-nido-6-CB^sub 9^H^sub 11^]^sup -^ ANION WITH AMINOPYRIDINES NC^sub 5^H^sub 4^NH^sub 2^ TO YIELD NEUTRAL arachno AND closo TEN-VERTEX MONOCARBABORANE DERIVATIVES
Collection of Czechoslovak Chemical Communications
; Reaction of NC^sub 5^H^sub 4^-2-NH^sub 2^ with the [6-Ph-nido-6-CB^sub 9^H^sub 11sup -^ anion (1) in the presence of hydrated FeCl^sub 3^ gives [6-Ph-9-(NC^sub 5^H^sub 4^-2-NH^sub 2arachno-6-CB^sub 9^H^sub 12^] (4) and thence [1-Ph-2-(NC^sub 5^H^sub 4^-2-NH^sub 2closo-1-CB^sub 9^H^sub 8^] (5), in
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Solid-Solid Reactions in the Ca^sub 3^(AsO^sub 4^)^sub 2^-Ca^sub 2^SiO^sub 4^-CaSO^sub 4^ Ternary System at Elevated Temperatures
Metallurgical and Materials Transactions
; Exploratory laboratory-scale tests were performed in order to identify the solid phases present in the Ca^sub 2^SiO^sub 4^-Ca^sub 3^(AsO^sub 4sub 2^ binary system and in the Ca^sub 2^SiO^sub 4^-Ca^sub 3^(AsO^sub 4^)2-CaSO^sub 4^-CaO system. A microanalysis study from slow-cooled samples suggests
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Modeling of the Solubilities of NiO/NiAl^sub 2^O^sub 4^ and FeO/FeAl^sub 2^O^sub 4^ in Cryolite Melts at 1300 K
Metallurgical and Materials Transactions
; Experiments to measure the solubilities of NiOTNiAl^sub 2^O^sub 4^ and FeO/FeAl^sub 2^O^sub 4^ were performed, and the results confirmed existing literature values. The solubilities of NiAl^sub 2^O^sub 4^ and FeAl^sub 2^O^sub 4^ in Al^sub 2^O^sub 3^-saturated cryolite melts at 1300 K were modeled
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Asthma Severity Is Associated with Body Mass Index and Early Menarche in Women
American Journal of Respiratory and Critical Care Medicine
; Asthma severity in relation to body mass index (BMI) has rarely been studied. The relation between BMI and asthma severity was studied by sex in 366 adults with asthma from the Epidemiological Study on the Genetics and Environment of Asthma, a case-control and family study on asthma. Factors
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Rhinovirus-induced interferon-[gamma] and airway responsiveness in asthma
American Journal of Respiratory and Critical Care Medicine
; The majority of asthma exacerbations are caused by respiratory infections, with rhinovirus (RV) being the most common virus. Recent evidence has suggested that decreased generation of IFN-[gamma] is associated with more severe colds and delayed elimination of virus. Whether the generation of
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Molecular Basis for the Dynamic Strength of the Integrin a^sub 4^B^sub 1^/VCAM-1 Interaction
Biophysical Journal
; ABSTRACT Intercellular adhesion mediated by integrin ?^sub 4sub 1^ and vascular cell adhesion molecule-1 (VCAM-1) plays a crucial role in both the rolling and firm attachment of leukocytes onto the vascular endothelium. Essential to the ?^sub 4sub 1^/VCAM-1 interaction is its mechanical strength
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Asthma Severity and Exposure to Occupational Asthmogens
American Journal of Respiratory and Critical Care Medicine
; Rationale: Severe asthma is a public health problem with limited information regarding preventable causes. Although occupational exposures have been implicated as important risk factors for asthma and asthma exacerbations, associations between occupational exposures and asthma severity have not
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