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Sequences downstream of the translation initiation codon are important determinants of translation efficiency in chloroplasts
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Sequences Downstream of the Translation Initiation Codon Are Important Determinants of Translation Efficiency in Chloroplasts'
The objective of this study was to determine if mRNA sequences downstream of the translation initiation codon are important for translation of plastid mRNAs. We have employed a transgenic approach, measuring accumulation of the neomycin phosphotransferase (NPTII) reporter enzyme translationally fused with 14 N-terminal amino acids encoded in the rbcL or atpB plastid genes. NPTII accumulation from wild-type and mutant rbcL and atpB segments was compared. We report ...
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A role for initiation codon context in choloroplast translation
Magazine article from: Plant Cell
; ...upstream of the initiation codon, base pairs...positioning and translation initiation (McCarthy...relative to the initiation codon (Bonham...quired for translation initiation, probably...downstream of the initiation codon have been...
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The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon.(Research)(ribonucleic acid)
Magazine article from: Virology Journal
; ...harboring multiple AUGs which are not used for initiation of translation. Previous investigations showed that translation initiation in BVDV, CSFV and HCV occurs by an internal ribosomal entry mechanism [1, 2, 3, 4, 5, 6, 7, 8...
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The katG mRNA of Mycobacterium tuberculosis and Mycobacterium smegmatis is processed at its 5' end and is stabilized by both a polypurine sequence and translation initiation.(Research article)
Magazine article from: BMC Molecular Biology
; ...Dalgarno sequence for translation initiation. Disruption of...coincides with the initiation codon of furA and is...upstream of katG initiation codon. The PPS is in bold and the translation initiation codon is boxed. The...
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Translation Initiation in Saccharomyces cerevisiae Mitochondria: Functional Interactions Among Mitochondrial Ribosomal Protein Rsm28p, Initiation Factor 2, Methionyl-tRNA-Formyltransferase and Novel Protein Rmd9p
Magazine article from: Genetics
; ...upstream of translation initiation, perhaps...coded mRNAs. TRANSLATION initiation appears to...both the initiation codon itself and...and cox3 initiation codon mutations...positive role in translation initiation that is enhanced...
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TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets.(Software)(Product/service evaluation)(Report)
Magazine article from: BMC Bioinformatics
; ...recognition of an AUG codon as a translation initiation site (TIS) depends on...context surrounding the initiation codon contributes to the control...which it is recognized as a translation initiation codon [5]. If the first initiation...
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Translation initiation region sequence preferences in Escherichia coli.(Research article)
Magazine article from: BMC Molecular Biology
; ...fMet-tRNA fMet , recognizes the translation initiation region (TIR) of the mRNA. This...contribute to its efficiency: (a) the initiation codon, which is most commonly AUG but...SD sequence and downstream of the initiation codon, which are often described as enhancers...
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Global analysis of microbial translation initiation regions.
Magazine article from: Journal of the Mississippi Academy of Sciences
; ...transcripts in their translation initiation process. This...Keywords: translation initiation, eubacterial...just 5' to the initiation codon (Shine and Dalgarno...mechanisms for translation initiation (Saito and Tomita...
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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity.(Research article)(Clinical report)
Magazine article from: Journal of Clinical Investigation
; ...Expression of eukaryotic translation initiation factor 4E (eIF4E) is...Introduction Eukaryotic translation initiation factor 4E (eIF4E) binds...UTR) to expose the translation initiation codon,enable ribosome loading...
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Leucine Regulates Translation Initiation in Rat Skeletal Muscle Via Enhanced elF4G Phosphorylation1,2
Magazine article from: The Journal of Nutrition
; ...regulatory agents, on key events in translation initiation in skeletal muscle and to elucidate...ability to augment key events in translation initiation and stimulate protein synthesis...that ultimately accelerate mRNA translation initiation. Examining the effect of leucine...
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 "Genome Biology (Online Edition)")
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On the functions of the h subunit of eukaryotic initiation factor 3 in late stages of translation initiation.(Research)
Magazine article from: Genome Biology (Online Edition)
; ...1] Background The eukaryotic translation initiation factor 3 (eIF3) consists of up...cap-dependent scanning mode of translation initiation [1, 2, 3, 4, 5]. The budding...protein kinases that control the translation initiation machinery, the target-of-rapamycin...
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