Circadian melatonin concentration rhythm is lost in pregnant women with altered blood pressure rhythm

From: Gynecological Endocrinology | Date: March 1, 2004| Author: Garbati, E; Giannubilo, S R; Turi, A; Tranquilli, A L | Copyright information

Key words: PREGNANCY, MELATONlN, PRE-ECLAMPSIA, AMBULATORY BLOOD PRESSURE MONITORING, CHRONOBIOLOGY

ABSTRACT

We assessed the correlation between the rhythm of melatonin concentration and circadian blood pressure patterns in normal and hypertensive pregnancy. Ambulatory 24-h blood pressure and blood samples every 4 h were monitored in 16 primigravidae who had shown an abnormal circadian blood pressure pattern (eight pre-eclamptic and eight normotensive) in pregnancy and 6-2 month...

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