Plant DNA Topoisomerases: Structure, Function, and Cellular Roles in Plant Development

From: Critical Reviews in Plant Sciences | Date: January 1, 2004| Author: | Copyright information

Regulation of the topological state of DNA is critical for cellular viability. DNA topoisomerases alter DNA topology and participate in nearly all events related to DNA metabolism such as replication, transcription, recombination, and chromosome segregation. Despite significant progress in our un derstanding of the structure, mechanism, and the role of topoisomerases in diverse cellular processes in bacteria, yeast, and animal systems, the roles of plant topoisomerases are poorly understood. In recent years expression studies, characterization of recombinant topoisomerases, and gene knockout ...

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