Viral Suppression of RNA Silencing in Plants From: In Vitro Cellular & Developmental Biology | Date: April 1, 2004| Author: Vance, V B; Mlotshwa, S; Pruss, G; Endres, M; Et al | Copyright Society for In Vitro Biology Spring 2004. Provided by ProQuest LLC.Copyright information

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RNA silencing is a remarkable type of gene regulation based on sequence-specific targeting and degradation of RNA. One key conserved feature of RNA silencing pathways in different organisms is that the process is triggered by dsRNA. The dsRNA is processed into short interfering RNAs (siRNAs) by the activity of a ribonuclease ??-like enzyme termed Dicer. The siRNAs incorporate into a large protein complex termed RISC and act as guides to direct the complex to target RNAs and effect...

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