Drug resistance study of Mycobacterium tuberculosis in Canads, February 1, 1993 to January 31, 1994 Canadian Journal of Public Health | September 1, 2000| | Copyright Canadian Public Health Association Sep/Oct 2000. Provided by ProQuest LLC. (Hide copyright information) Copyright

ABSTRACT

Objective: To estimate the prevalence of resistance of Mycobacterium tuberculosis to first-line antituberculosis drugs in Canada.

Methods: M. tuberculosis isolates from one third of all culture-positive tuberculosis (TB) cases diagnosed between February 1, 1993 to January 31, 1994 in Canada were collected prospectively. Proportion of drug-resistant isolates and the factors related to drug resistance were measured.

Results: Of 458 study cases, 40 (8.7%) had resistance to at least one first=line antituberculosis drug, of which 5.9% had mono-resistance, 0.7% had multidrug-resistance ...

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