Effect of Caffeine Intake on Myocardial Hyperemic Flow Induced by Adenosine Triphosphate and Dipyridamole The Journal of Nuclear Medicine | May 1, 2004| | Copyright Society of Nuclear Medicine May 2004. Provided by ProQuest LLC. (Hide copyright information) Copyright

The aims of this study were (a) to compare absolute myocardial blood flow (MBF) during adenosine triphosphate (ATP) infusion with that after dipyridamole administration without caffeine intake and (b) to evaluate the effect of caffeine intake on the hyperemic flow induced by these coronary vasodilator agents. Methods: MBF was quantified with ^sup 15^O-labeled water and PET at rest, during ATP infusion (0.16 mg/kg/min for 9 min), and after dipyridamole administration (0.56 mg/kg over 4 min) after a 24-h abstinence from caffeine (baseline evaluation) in 10 healthy volunteers. Within 2 wk, the ...

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