ANTAGONISTIC EFFECTS OF SIMULTANEOUS EXPOSURE OF ERGOT ALKALOIDS ON KIDNEY ADENOSINE TRIPHOSPHATASE SYSTEM

In Vitro Cellular & Developmental Biology | September 1, 2003| | Copyright

SUMMARY Much of the research on fescue toxicosis has concentrated on evaluating animal response to grazing endophyte-infected (E+) versus endophyte-free tall fescue or the effects of single toxins such as ergonovine (EN), ergovaline (EV), or ergotamine (ET) on animal performance. Such approaches have eliminated the opportunity to test the possible additive, synergistic, or antagonistic interactions of one or more ergot alkaloids with the other ergot alkaloids found in E+ tall fescue. This study was conducted to determine the effects of simultaneous exposure of pairs of EN, EV, and ET on the ...

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