|
Tumor Localization of 16[beta]-^sup 18^F-Fluoro-5[alpha]-Dihydrotestosterone Versus ^sup 18^F-FDG in Patients with Progressive, Metastatic Prostate Cancer
|
This trial was an initial assessment of the feasibility, in vivo targeting, and biokinetics of 16[beta]-^sup 18^F-fluoro-5[alpha]-dihydrotestosterone (^sup 18^F-FDHT) PET in patients with metastatic prostate cancer to assess androgen receptor expression. Methods: Seven patients with progressive clinically metastatic prostate cancer underwent ^sup 18^F-FDG and ^sup 18^F-FDHT PET scans in addition to conventional imaging methods. Three patients had their studies repeated 1 mo later, 2 while on ...
Related newspaper, magazine, and journal articles from HighBeam Research
|
|
PET Imaging of GRP Receptor Expression in Prostate Cancer
The Journal of Nuclear Medicine
; An the United States alone, 1 in 6 men will be diagnosed with prostate cancer over the course of their lifetimes, with 31,000 dying each year from the disease. Imaging prostate cancer remains a major challenge in nuclear medicine. ^sup 18^F-FDG, the most commonly used radiotracer for the detection
|
|
|
1-^sup 11^C-Acetate Kinetics of Prostate Cancer
The Journal of Nuclear Medicine
; ^sup 18^F-FDG is in widespread use in cancer imaging but has limited utility in staging and monitoring of prostate cancer. 1-^sup 11^C-Labeled acetate, a substrate for the citric acid cycle, is superior. The kinetics of prostate tumors were investigated. Methods: Ten patients with primary prostate
|
|
|
(11)C-acetate PET imaging of prostate cancer
The Journal of Nuclear Medicine
; ^sup 11^C-Acetate can act as a probe of tissue metabolism through entry into catabolic or anabolic metabolic pathways as mediated by acetyl-coenzyme A. The uptake of ^sup 11^C-acetate in prostate cancer was investigated to determine whether this tracer has potential in tumor identification.
|
|
|
PET imaging of prostate cancer using carbon-11-choline
The Journal of Nuclear Medicine
; Prostate cancer is difficult to visualize using current techniques. Recently, ^sup 31^P magnetic resonance spectroscopy has revealed that the tumor, in general, is characterized by an increased uptake of choline into the cell to meet increased synthesis of phosphatidylcholine, an important cell
|
|
|
Development of (18)F-fluoroethylcholine for cancer imaging with PET: Synthesis, biochemistry, and prostate cancer imaging
The Journal of Nuclear Medicine
; The effectiveness of ^sup 11^C-choline PET in detecting various cancers, including prostate cancer, is well established. This study was aimed at developing an ^sup 18^F-substituted choline analog, ^sup 18^F-fluoroethylcholine (FECh), as a tracer of cancer detection. Methods: No-carrier-added ^sup
|
