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Approaches to Enhance the Efficacy of DNA Vaccines
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ABSTRACT: DNA vaccines consist of antigen-encoding bacterial plasmids that are capable of inducing antigen-specific immune responses upon inoculation into a host. This method of immunization is advantageous in terms of simplicity, adaptability, and cost of vaccine production. However, the entry of DNA vaccines and expression of antigen are subjected to physical and biochemical barriers imposed by the host. In small animals such as mice, the host-imposed impediments have not prevented DNA vacc...
Related newspaper, magazine, and journal articles from HighBeam Research
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PowderJect, GlaxoSmithKline Initiate Clinical Study.(Brief Article)
Nanoparticle News
; PowderJect Pharmaceuticals, plc and its wholly owned subsidiary, PowderJect Vaccines, Inc, have initiated a clinical trial to support the development of a DNA immunotherapeutic to treat hepatitis-B using the needle-free PowderJect system. The study is sponsored by GlaxoSmithKline as part of a major
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 "Rocky Mountain News (Denver, CO)")
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HIV VACCINE ON TRIAL 20 COLORADANS TO BE AMONG VOLUNTEERS FOR 1ST HUMAN TESTS OF DRUG DESIGNED TO CONTAIN, SUPPRESS VIRUS.(Local)
Rocky Mountain News (Denver, CO)
; Byline: Jim Erickson News Science Writer Next month, 20 Coloradans will volunteer for the first human trials of an HIV vaccine designed to contain and suppress ...
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DNA technology holds the hope of a new shot at vaccines. (Originated from Knight-Ridder Newspapers)
Knight Ridder/Tribune News Service
; PHILADELPHIA _ More than four decades after scientists first described the structure of DNA, the fundamental building block of life, researchers are at the frontier of a new revolution: using that same material, DNA, to vaccinate people against everything from the flu to the AIDS virus. The
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Vaccine tattooing proves effective
Dermatology Times
; Delivery spurs greater immunity compared to intramuscular injection National Report - Skin-tattooing devices may be associated more with vanity than vaccines, but in the hands of researchers in Germany and England, the devices are indeed showing promise as valuable delivery vehicles for important
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 "Birmingham Evening Mail (England)")
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CITY VACCINE HOPE FOR CANCER CURE.(News)
Birmingham Evening Mail (England)
; Byline: PAULA MARSH A NEW generation of vaccines which could revolutionise health care and provide a cure for cancer are being developed at Aston University. Dr Yvonne Perrie has become the first person in the UK to investigate using DNA vaccines to protect against flu, hepatitis and cancer. Dr
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