Use of Polymerase Chain Reaction to Diagnose Tuberculous Arthritis From Joint Tissues and Synovial Fluid

From: Archives of Pathology & Laboratory Medicine | Date: February 1, 2004| Author: | Copyright information

* Context.-Tuberculosis of the joints and bones is a significant worldwide problem, often leading to joint and bone destruction. The diagnosis of this disease manifestation is difficult.

Objective.-To assess the role of conventional diagnostics compared to polymerase chain reaction applied to samples obtained at arthroscopy.

Design.-This was an open observational study that was blinded to the microbiologist, histopathologist, and molecular biologist responsible for assessing the main outcome measures.

Patients.-Seven patients (8 samples) with joint and bone tuberculosis and 14 patients (16 ...

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