Interactions of the M2[delta] Segment of the Acetylcholine Receptor with Lipid Bilayers: A Continuum-Solvent Model Study

From: Biophysical Journal | Date: December 1, 2003| Author: | Copyright information

ABSTRACT M2[delta], one of the transmembrane segments of the nicotinic acetylcholine receptor, is a 23-amino-acid peptide, frequently used as a model for peptide-membrane interactions. In this and the companion article we describe studies of M2[delta]-membrane interactions, using two different computational approaches. In the present work, we used continuum-solvent model calculations to investigate key thermodynamic aspects of its interactions with lipid bilayers. M2[delta] was represented in atomic detail and the bilayer was represented as a hydrophobic slab embedded in a structureless ...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

Delta, Northwest file bankruptcy
; Delta Air Lines Inc. and Northwest Airlines Corp., hobbled by high...carriers to enter Chapter 11 since the 2001 terrorist attacks. Delta's late afternoon filing included its low-fare subsidiary Song and was followed shortly after by Northwest's. Delta's total debt is about $28.3 billion, and it listed ...
Delta gains Net altitude ; No. 3 airline debuts site for big companies, plans small-business hub, wireless initiative.(Brief Article)
; Delta Air Lines Inc., the nation's No. 3 carrier, is making a big...for small businesses, as well as a wireless booking system. Delta's Internet moves come amid a backdrop of feverish consolidation...increasingly viewed as a necessity to compete. Moreover, Delta's ventures could make it a more attractive ...
Delta files Chapter 11 plan that would keep it a standalone company, rejects USAir bid
; ATLANTA -- Delta Air Lines Inc. filed a reorganization plan...advisers have determined that a reorganized Delta will have a consolidated equity value of...the plan would result in a recovery by Delta's unsecured creditors of roughly 63 percent...
COMAIR DRIVING DELTA'S GROWTH.(NEWS)
; Delta Air Lines' growth in the next five years at Cincinnati/Northern Kentucky International Airport will come from Comair, its booming subsidiary, Delta officials said. Delta has not grown as expected at its second-largest hub at the airport in Boone County, mainly because the airline...
DELTA LOOKING TO AX AS MANY AS 9,000 JOBS
; Delta Air Lines Inc. outlined plans yesterday to cut up to 9,000...red ink and emerge from bankruptcy protection. How many of Delta's 1,000 jobs at Logan International Airport will be affected has yet to be determined, company officials said. Delta has only begun what will likely be a months-long process...
Delta focusing on customer service
; ATLANTA -- Delta Air Lines, trying to fight its low-cost...the past: customer service. For years, Delta, which operates a hub at Salt Lake City...AirTran, is one of the low-cost carriers Delta is fighting. "They've lost it, and customers...
DELTA'S TERMINAL LEASES UP IN THE AIR
; Delta Air Lines Inc. is widely expected to spare Boston from its deepest cutbacks in service...slash service. But in fine print of the bond deal Massport floated in August 2001 for Delta to build the new terminal, Massport agreed to waive that right in the Delta terminal until five years after the airline ...
Delta joins Northwest in merger
; ATLANTA - Delta Air Lines Inc. and Northwest Airlines Corp., squeezed...of both companies gave the deal the go-ahead Monday. Delta said the combined airline, which will be called Delta, will have an enterprise value of $17.7 billion. It will...
Delta earnings better than expected.(The Dallas Morning News)
; Delta Air Lines lost $326 million in the third quarter and will...year-earlier loss of $2.13 per share. Removing one-time charges, Delta lost $212 million, or $1.75 a share. That number beat Wall Street's expectations that Delta would lose $1.84 per share. The carrier, however, told investors...
Delta plan calls for flying solo
; ATLANTA -- Delta Air Lines filed a reorganization plan Tuesday...worst of all potential merger partners," Delta Chief Executive Gerald Grinstein said during...than US Airways, saying later Tuesday that Delta would review any other bids. But he said...