Plasma Leptin Is Regulated Predominantly by Nutrition in Preruminant Lambs1 From: The Journal of Nutrition | Date: December 1, 2003| Author: Bell, Alan W; Boisclair, Yves R; Greenwood, Paul L; Ehrhardt, Richard A | Copyright American Institute of Nutrition Dec 2003. Provided by ProQuest LLC.Copyright information

ABSTRACT In juvenile and mature animals, the plasma concentration of leptin is regulated by adiposity and nutrition. However, the timing of these influences on plasma leptin, and their relative importance in early postnatal life, are unknown. We investigated these plasma leptin influences in sheep, a species characterized during fetal life by leanness and insensitivity of leptin to variation in maternal nutrition. Small and large neonatal lambs were randomly assigned to either a diet sustaini...

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