The use of Polymerase Chain Reaction for detection of joint arthroplasty infections

From: Journal of Bone and Joint Surgery | Date: January 1, 2003| Author: | Copyright information

Introduction: Infection constitutes a serious complication of joint arthroplasty, with an incidence of 1-2% after primary arthroplasty and even higher after revision procedures. Detection of low-grade infection in a prosthetic joint can often be very difficult, with huge implications on the subsequent treatment, cost and patient morbidity. Revision of an unrecognised infected arthroplasty may lead to less satisfactory results in a high proportion of cases. We utilized Polymerase Chain Reaction, a molecular biology technique to detect bacterial DNA from the synovial fluid of patients ...

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