Presence of human herpesvirus 8 DNA sequences in renal transplantation-associated pleural Kaposi sarcoma

From: Archives of Pathology & Laboratory Medicine | Date: December 1, 1999| Author: Gomez-Roman, J Javier; Ocejo-Vinyals, J Gonzalo; Sanchez-Velasco, Pablo; Leyva-Cobian, Francisco; Val-Bernal, J Fernando | Copyright information

Objective.-To describe one case of symptomatic skin and pleural Kaposi sarcoma (KS) associated with kidney transplantation. Diagnosis was supported by morphologic study and human herpesvirus 8 (HHV-8) detection in both tissues. Pulmonary involvement was not present.

Design.-The presence of HHV-8 DNA sequences was proved using polymerase chain reaction (PCR), Southern blot hybridization, and in situ hybridization.

Setting.-Human herpesvirus 8 is found in most KS from patients w...

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