Reverse-transcription polymerase chain reaction detection of the enteroviruses: Overview and clinical utility in pediatric enteroviral infections

From: Archives of Pathology & Laboratory Medicine | Date: December 1, 1999| Author: | Copyright information

* Objective.-This review focuses on commercial and inhouse-developed reverse-transcription polymerase chain reaction (RT-PCR) assays used for the detection of enteroviral infections. In addition to providing details on the performance of RT-PCR, its specificity, and sensitivity, the clinical utility of this diagnostic method with specific reference to its impact on hospitalization and cost savings is addressed.

Data Sources.-MEDLINE was searched for reports relating to RT-PCR detection of the enteroviruses in adults and children. The search was restricted to studies reported in English ...

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