Reboxetine: A selective norepinephrine reuptake inhibitor for the treatment of major depression

From: Formulary | Date: November 1, 1999| Author: | Copyright information

ABSTRACT

Reboxetine is the first of a new class of drugs known as selective norepinephrine reuptake inhibitors for the treatment of major depression. It is expected to be launched at the end of 1999. Comparative clinical trials show reboxetine to be as effective as imipramine and desipramine in adults and the elderly. Additional studies show it to be as effective as fluoxetine in depressed patients overall and more effective than fluoxetine in the severely depressed. Reboxetine appears to lack the cognitive and cardiovascular adverse effects of TCAs and to be associated with fewer ...

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