|
Saving the breath condensate approach
|
To the Editor:
I read with interest the editorial by Gaston (1) that suggests that breath condensate analysis might be "worth studying, after all." This hopeful viewpoint is based on the study of Corradi and colleagues (2), which showed that condensate concentrations of glutathione decreased in asthma exacerbations, whereas those of malondialdehyde increased. Gaston then questions the need for the "mathematical interpretation" in our earlier publication (3), which emphasized the necess...
Related newspaper, magazine, and journal articles from HighBeam Research
|
"Acidopnea" and the dictionary / From the authors
American Journal of Respiratory and Critical Care Medicine
; "ACIDOPNEA" AND THE DICTIONARY To the Editor: A recent editorial by Gaston and Hunt (1) coins a new word, "acidopnea" ("acidopnoea" in British usage), while reviewing the work of Kostikas and colleagues (2) and others. I hope the word will not enter general usage. The word is scientifically
|
|
Metabolomics in Exhaled Breath Condensates/From the Authors
American Journal of Respiratory and Critical Care Medicine
; To the Editor: The intriguing article by Dr. Carraro and colleagues (1) concerning nuclear magnetic resonance (NMR) measurements of exhaled breath condensate (EBC) for distinguishing patients with asthma from normal subjects suggests that this procedure may be used as an "artificial nose" for
|
|
Exhaled Breath Condensate pH
American Journal of Respiratory and Critical Care Medicine
; To the Editor: In an editorial (1) that accompanied our article on the effect of volatile acids and bases released from the mouth (2), Dr. Hunt has acknowledged that these can have a significant influence on exhaled breath condensate (EBC) pH, but believes that EBC pH primarily reflects pulmonary
|
|
Breath condensate analysis: Perhaps worth studying, after all
American Journal of Respiratory and Critical Care Medicine
; My breath is corrupt, may days are extinct, the grave is ready for me. -Job 17:1 In this issue of AJRCCM (pp. 395-399), Corradi and coworkers (1) present evidence that breath condensate analysis identifies changes in the reduction/oxidation (redox) chemistry of water exhaled by children with acute
|
|
Further discussion on breath condensate analysis
American Journal of Respiratory and Critical Care Medicine
; In this issue of AJRCCM (pp. 1380-1386), Corradi and coworkers (1) report a new method for determining aldehydes in exhaled breath condensates based on derivatization with 2,4-dinitrophenylhydrazine and analysis by liquid chromatography coupled with atmospheric pressure chemical ionization mass
|
|
If It Smells Like a Duck, It Might Be an Asthma Subphenotype
American Journal of Respiratory and Critical Care Medicine
; Now beginning to be heard above the constant din of powerful marketing efforts to the converse, a growing wave of physicians have been shouting "asthma is not a diagnosis." Indeed, asthma is but a symptom, categorically on par with diarrhea. Imagine determining the optimum treatment strategy for
|
|
Exhaled Breath Condensate Detects Markers of Pulmonary Inflammation after Cardiothoracic Surgery
American Journal of Respiratory and Critical Care Medicine
; Cardiac surgery using cardiopulmonary by-pass and, to a greater extent, lung resection, causes acute lung injury that is usually subclinical. Analysis of mediators in exhaled breath condensate is a promising means of monitoring inflammation in a variety of airway diseases but the contribution of
|
|
Increased leukotriene B^sub 4^ and interleukin-6 in exhaled breath condensate in cystic fibrosis
American Journal of Respiratory and Critical Care Medicine
; Chronic neutrophilic airway inflammation is an important feature of cystic fibrosis (CF). Noninvasive inflammatory markers may be useful in monitoring CF. Leukotriene B^sub 4^ (LTB^sub 4^) and interleukin (IL)-6 are inflammatory mediators that are increased in chronic neutrophilic inflammation. The
|
|
Metabolomics Applied to Exhaled Breath Condensate in Childhood Asthma
American Journal of Respiratory and Critical Care Medicine
; Rationale: Metabolomic analysis provides biochemical profiles of low-molecular-weight endogenous metabolites in biological fluids. Objectives: The aim of this study was to assess the feasibility of nuclear magnetic resonance (NMR)-based metabolomic analysis applied to exhaled breath condensate
|
|
Students puff for pollution study
The Press
; Breath condensate and urine samples from 80 Christ's College boarders will help medical researchers analyse the effects of pollution on teenagers. Researchers approached Christ's College for volunteers because it was believed boarders would provide a unique sample. The students live and attend
|