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Epinephrine transiently increase amino acid disappearance to lower amino acid levels in humans
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ABSTRACT. Background: Infusion of epinephrine decreases plasma amino acid concentrations. However, the mechanism by which this decrement occurs is not well characterized.
Methods: Epinephrine was infused (40 ng/kg/min) for 2 hours into eight normal healthy adults. The essential amino acid tracers L-[1-^sup 13^C] leucine and L-[phenyl-^sup 2^H^sub 5^]phenylalanine were infused before and during the epinephrine infusion and blood samples obtained to determine amino acid rates of appearance and disappearance from the time course of change in amino acid concentration and tracer enrichments.
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