Factor V Leiden and venous thromboembolism: Risk associated with hormone replacement therapy

From: Journal of the American Academy of Nurse Practitioners | Date: October 1, 2003| Author: | Copyright information

Purpose

To determine the risk-benefit ratio of hormone replacement therapy (HRT) and the cost-effectiveness of screening in perimenopausal and postmenopausal women who are carriers of factor V Leiden, as well as to provide evidence-based clinical recommendations for the primary care provider.

Data Sources

Databases searched included EMBASE, BIOSIS, MEDLINE, CINAHL, PubMed, SciSearch, and the Cochrane Database. Two reviewers extracted, reviewed, and concurred upon relevant evidence identified in the databases.

Results

Results confirmed that all women have a higher risk for the development of ...

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