Clonal analysis of non-toxigenic Vibrio cholerae 01 associated with the outbreak of cholera

From: Indian Journal of Medical Research | Date: June 1, 1999| Author: | Copyright information

Accepted May 20,1999

We examined the clonal relationships among eight clinical isolates of non-toxigenic (NT) V cholerae Ol associated with a cluster of cases of cholera in Warangal, Andhra Pradesh in south India and compared their relatedness to toxigenic O1 strains of classical and ElTor biotypes and with 0139 Bengal strains of If cholerae by pulsed-field gel electrophoresis (PFGE). Phylogentic analysis of the NotI restriction fragment length polymorphism showed that all the NT. lf cholerae O1 strains formed a tight cluster with more than 80 per cent similarity. Interestingly, the NT V ...

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