|
Immunosuppressive effects of silicon phthalocyanine photodynamic therapy
|
ABSTRACT
The purpose of this study was to determine if silicon phthalocyanine 4 (Pc 4), a second-generation photosensitizer being evaluated for the photodynamic therapy (PDT) of solid tumors, was immunosuppressive. Mice treated with Pc 4 PDT 3 days before dinitrofluorobenzene sensitization showed significant suppression of their cell-mediated immune response when compared to mice that were not exposed to PDT. The response was dose dependent, required both Pc 4 and light and occurred at a skin site remote from that exposed to the laser. The immunosuppression could not be reversed by in vivo ...
Related newspaper, magazine, and trade journal articles from HighBeam Research
(Including press releases, facts, information, and biographies)
|
|
Association between the photodynamic loss of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy[para]
; ...ABSTRACT We have reported that photodynamic therapy (PDT) using the photosensitizer phthalocyanine (Pc) 4 and red light damages...more or less responsive to Pc 4-PDT. In this study we...from apoptosis caused by Pc 4-PDT. In contrast, Bcl...relative resistance of cells to Pc 4-PDT, as ...
|
|
|
Apoptosis Mechanisms Related to the Increased Sensitivity of Jurkat T-cells vs A431 Epidermoid Cells to Photodynamic Therapy with the Phthalocyanine Pc 4[dagger][double dagger]
; ...cell lines was linear with Pc 4 concentration and similar...differential aggregation of Pc 4 in the two cell types...by confocal microscopy, Pc 4 localized to mitochondria...effects of phthalocyanine photodynamic therapy (Pc 4-PDT) than were A431 cells...in A431, cells exposed to ...
|
|
|
The peripheral benzodiazepine receptor in photodynamic therapy with the phthalocyanine photosensitizer Pc 4
; ...Receptor in Photodynamic Therapy with the Phthalocyanine...Photosensitizer Pc 4(para) ABSTRACT...photosensitizers for photodynamic therapy (PDT), which...phthalocyanine (Pc) photosensitizer...phosphate-buffered saline; Pc, phthalocyanine; PDT, photodynamic ...
|
|
|
Phthalocyanine 4 (Pc 4) photodynamic therapy of human OVCAR-3 tumor xenografts
; ABSTRACT Photodynamic therapy (PDT) is a cancer treatment...photosensitizer, light and oxygen. Photodynamic therapy with Photofrin has been...use. The photosensitizer Pc 4 (HOSiPcOSi[CH3]2[CH...animals receiving 1.0 mg/kg Pc 4 and light, six (60...from animals treated with Pc 4 ...
|
|
|
Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo
; ...Singlet Oxygen Generated by Photodynamic Therapy in Cells In Vitro and Tissues...cytotoxic agent involved in photodynamic therapy (PDT). Measurement of...phthalocyanine (AlS^sub 4^Pc) and Photofrin. Measurements...parametric oscillator; PDT, photodynamic therapy; PMT, ...
|
|
Photodynamic therapy.(Photodynamic therapy T Patrice)(Book Review)
; Photodynamic therapy T Patrice (ed) Cambridge; Royal Society...seems appropriate when considering photodynamic therapy. Churchill was 29 years old when, in 1904, the term photodynamic therapy was first used by a professor called...
|
|
Nonsurgical Tx Benefits Paget's Disease.(photodynamic therapy for Paget's disease)
; WASHINGTON -- Photodynamic therapy holds great promise as an...local anatomy and function. Photodynamic therapy using topical [delta]-aminolevulinic...1995 to 2001 has now shown photodynamic therapy to be beneficial for this...
|
|
|
Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1
; ...used to compare the effects of photodynamic therapy (PDT) with those of the apoptotic...forming ability by 90%; PDT, photodynamic therapy; ROS, reactive oxygen species...membrane potential. INTRODUCTION Photodynamic therapy (PDT) is a procedure whereby...Korbelik, J. Moan and Q. Peng ...
|
|
Photodynamic Therapy Slows Esophageal Dysplasia's Progression.
; ATLANTA -- Photodynamic therapy reduces the long-term risk...patients who were treated with photodynamic therapy primarily for high-grade...Center, Knoxville, Tenn. For photodynamic therapy, the photo-sensitizing agent...
|
|
Photodynamic therapy for the palliation of esophageal cancer: Expensive endoscopic technique or inexpensive cancer treatment? / In reply
; ...description of photodynamic therapy (PDT) as relatively...external-beam radiation. Photodynamic therapy with porfimer...Lightdale CJ. Role of photodynamic therapy in the management...Henderson BW, et al. Photodynamic therapy. J Natl Cancer...oncoprotein during ...
|
For more facts and information,
see all results
