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Hesperetin glucuronide, a photoprotective agent arising from flavonoid metabolism in human skin fibroblasts[para]
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ABSTRACT
There is considerable interest in the biological properties of flavonoids in terms of their antioxidant and cytoprotective actions. The interaction of the flavanone hesperetin with human skin fibroblasts (FEK4) has revealed the potential for metabolism to hesperetin glucuronide and its subsequent extrusion. As a consequence of this observation, the effectiveness of hesperetin glucuronides, in comparison with that of the aglycone form, in protecting against UV-A radiation has been investigated. The results indicate that hesperetin glucuronides, but not hesperetin, protect against ...
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Cell death in the unicellular chlorophyte Dunaliella tertiolecta. A hypothesis on the evolution of apoptosis in higher plants and metazoans
; ...metazoans and higher plants. Although cell death processes have been reported in unicellular...Dunaliella tertiolecta undergoes a form of cell death reminiscent of apoptosis in metazoans. Many morphological criteria of apoptotic cell death were met, including an increase in ...
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DPL-1 DP, LIN-35 Rb and EFL-1 E2F Act With the MCD-1 Zinc-Finger Protein to Promote Programmed Cell Death in Caenorhabditis elegans
; ...ced-3 play major roles in programmed cell death in Caenorhabditis elegans. To identify...we sought mutations that confer strong cell-death defects in a genetically sensitized mutant...screened for mutations that enhance the cell-death defects caused by a partial loss-of-function...
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Spotted leaf11, a Negative Regulator of Plant Cell Death and Defense, Encodes a U-Box/Armadillo Repeat Protein Endowed with E3 Ubiquitin Ligase Activity(W)
; ...previously shown to display a spontaneous cell death phenotype and enhanced resistance to...ubiquitination system in the control of plant cell death and defense. INTRODUCTION In multicellular organisms, cell death can occur as either a physiological...
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Cell death in the central nervous system: Therapeutic possibilities?
; ...been produced regarding the study of cell death. That cells die in different ways has...recently, with the genetic dissection of cell death in a model system, the nematode. This...realization of how common physiologic cell death is-from morphological modeling such as...
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The science of cellular suicide. (research on cell death)
; ...are born and old ones die. Moreover, cell death can occur in predictable patterns, especially...is the actual mechanism of programmed cell death? Do cells simply wither away when their...Chapel Hill, are exploring mechanisms of cell death in the tobacco hawkmoth. The moth is...
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Arabidopsis ACCELERATED CELL DEATH2 Modulates Programmed Cell Death[W]
; ...ACD2) modulates the amount of programmed cell death (PCD) triggered by Pseudomonas syringae...PCD-inducing events. INTRODUCTION Programmed cell death (PCD) is a common response to pathogens...absence of the HR, P. syringae also causes cell death (susceptible cell ...
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Preexisting systemic acquired resistance suppresses hypersensitive response-associated cell death in Arabidopsis hrl1 mutant
; ...Suppresses Hypersensitive Response-Associated Cell Death in Arabidopsis hrl1 Mutant1 The hypersensitive...hrl1suppresses avirulent pathogen-induced HR cell death. Furthermore, the high PRA expression...expression of the nahG gene. The rescue of HR cell death in hrl1 npr1 and in hrl1 ...
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A Genetic Screen Identifies New Regulators of Steroid-Triggered Programmed Cell Death in Drosophila
; ...of this steroid-triggered programmed cell death response. Pupal lethal mutants were screened...identification of mutations in known cell death regulators, E74 and hid, as well as multiple...regions or genes previously associated with cell death. Five mutants display defects in the...
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Programmed cell death in development and defense
; THE CONCEPT OF PROGRAMMED CELL DEATH (PCD) CAME FROM PLANTS Around the...number of physiologists studying cell death in various contexts for the rest...Plant physiologists knew that cell death is essential for normal development...
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Cell death processes during expression of hybrid lethality in interspecific F(1) hybrid between Nicotiana gossei domin and Nicotiana tabacum
; ...prompt lysis of cell components during cell death. Membrane disruption and DNA degradation...suggesting that a putative factor inducing cell death diffused into surrounding cells from...the cytoplasm of cells and that massive cell death eventually led to the loss of the hybrid...
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