Technetium HMPAO SPECT study in dementia with Lewy bodies, Alzheimer's disease and idiopathic parkinson's disease

From: The Journal of Nuclear Medicine | Date: June 1, 1999| Author: | Copyright information

The aim of this study was to compare the regional cerebral blood flow measurements studied by SPECT in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) to determine the contribution of SPECT to the differential diagnosis of these two diseases. Methods: SPECT analysis with ^sup 99m^Tc-hexamethyl propyleneamine oxime (HMPAO) was performed in 20 patients with probable DLB, 20 patients with probable AD and 20 patients with idiopathic Parkinson's disease (IPD). Ten pairs of regions of interest were analyzed. Tracer uptake was expressed as a corticocerebellar activity ratio. Results: ...

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