Simulated epidural test doses using adrenaline and adrenaline/clonidine in sevoflurane-anaesthetized children

Anaesthesia and Intensive Care | August 1, 2003| | Copyright

SUMMARY

A pilot study was conducted using a simulated epidural test dose to ascertain the effects adrenaline, adrenaline/clonidine mixture, and clonidine alone on the accepted criteria for determining the occurrence of an epidural intravascular injection. Seventy-five ASA 1 or 2 children aged from six months to twelve years were sequentially allocated to one of three groups: group A: adrenaline 0.5 [mu]g/kg, group AC: adrenaline 0.5 [mu]g/kg and clonidine 0.3 [mu]g|kg, and group C: clonidine 0.3 [mu]g/kg. Effects on heart rate, T-wave amplitude and systolic blood pressure were determined ...

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