Verocytotoxin-producting Escherichia coli O157: Public health and microbiological significance

From: British Journal of Biomedical Science | Date: June 1, 1998| Author: | Copyright information

Abstract: Escherichia coli 0157 was recognised as a human pathogen in the late 1970s, its public health significance being recognised in 1982 when it was implicated in a large outbreak of infection associated with a fast-food restaurant in North America. Incidence of infection in the population is relatively low compared to other enteric pathogens; however, this organism causes a spectrum of disease increasing in severity from a mild diarrhoeal illness to haemorrhagic colitis, haemolytic uraemic syndrome (HUS) and, in some cases, death. Production of verocytotoxin and intimin, and the ...

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