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Agrylin: Treatment of thrombocythemia due to myeloproliferative disorders
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Treatment of thrombocythemia due to myeloproliferative disorders Anagrelide HCI
Roberts Laboratories Inc
The FDA has expanded the indication for the platelet-reducing agent anagrelide HCl capsules from patients with essential thrombocythemia to patients with thrombocythemia secondary to myeloproliferative disorders; in this expanded patient population the agent is again indicated to reduce elevated platelet counts and the risk of thrombosis and to ameliorate associated symptoms, including thrombohemorrhagic events.
Approval was based on an expansion of the three clinical trials cited for ...
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Current Management of the Myeloproliferative Disorders: A Case-Based Review
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bcr/abl-Negative, Classic Myeloproliferative Disorders: Diagnosis and Treatment
; ...hematopoiesis; ET = essential thrombocythemia; Hct = hematocrit...metaplasia; MPD = myeloproliferative disorders; PV = polycythemia...interrelationship between essential thrombocythemia (ET), polycythemia...and MMM. ESSENTIAL THROMBOCYTHEMIA DIAGNOSIS...
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The JAK2^sup V617F^ Tyrosine Kinase Mutation in Myeloproliferative Disorders: Status Report and Immediate Implications for Disease Classification and Diagnosis
; ...proteins. The myeloproliferative disorders (MPD), a...polycythemia vera, essential thrombocythemia, myelofibrosis...receptor; ET = essential thrombocythemia; FISH = fluorescent...metaplasia; MPD = myeloproliferative disorders; PCR = polymerase...Organization ...
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BCR/ABL-Negative Chronic Myeloproliferative Disorders: JAK2 Mutation and Beyond
; ...treatment of classic BCR/ABL-negative chronic myeloproliferative disorders (CMPDs) (ie, essential thrombocythemia, polycythemia vera, and chronic idiopathic myelofibrosis). Each of these myeloproliferative disorders represents a multipotent hematopoietic...clinical situations. ...
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A long-term retrospective study of young women with essential thrombocythemia
; ...women younger than 50 years with essential thrombocythemia. * Patients and Methods: We retrospectively...records of all patients with essential thrombocythemia evaluated at Mayo Clinic, Rochester...years; range, 18-48 years) with essential thrombocythemia. The diagnosis was based on ...
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Polycythemia Vera and Essential Thrombocythemia.
; Polycythemia vera and essential thrombocythemia are chronic myeloproliferative...polycythemia vera and essential thrombocythemia. Polycythemia vera...receive hydroxyurea. Essential thrombocythemia is diagnosed after...
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University of Illinois at Chicago Receives $20 Million National Cancer Institute Grant to Research Blood Disorders.
; ...establish the Myeloproliferative Disorders Research Consortium...for specific myeloproliferative disorders, said Hoffman...focus on two myeloproliferative disorders, polycythemia...patients with myeloproliferative disorders. Three of...disorders. ...
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; ...Pathologic Diagnosis: Essential Thrombocythemia With Ringed Sideroblasts...bone marrow.1,2 In myeloproliferative disorders, hematopoiesis...by cytopenia.1 Essential thrombocythemia is a chronic myeloproliferative...the bone marrow.3 Essential thrombocythemia usually is ...
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The Myelodysplastic Syndromes and Myeloproliferative Disorders
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