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Fluoroquinolone more effective against gram-positive bacteria
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Battling conjunctivitis
Gatifloxacin found to be more active in vitro against ocular isolates than older agents
Fort Lauderdale, FL-Gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan) shows clearly improved activity against commonly encountered gram-positive ocular bacteria in vitro compared with older fluoroquinolones. This fourth-generation fluoroquinolone received FDA approval in March (see related article, Ophthalmology Times, May 1 issue, Page 1).
Many gram-posit...
Related newspaper, magazine, and journal articles from HighBeam Research
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Fluoroquinolone more effective against gram-positive bacteria
Ophthalmology Times
; Battling conjunctivitis Gatifloxacin found to be more active in vitro against ocular isolates than older agents Fort Lauderdale, FL-Gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan) shows clearly improved activity against commonly encountered gram-positive ocular bacteria in vitro compared
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TRUST/Ocular TRUST data document durability of fluoroquinolone activity nationwide
Ophthalmology Times
; Monitoring antimicrobial resistance Reviewed by Penny A. Asbell, MD, FACS, MBA New York-In a subspecialty such as ophthalmology, isolated case reports of antimicrobial resistance can raise concern but are not the best barometer of overall trends in resistance. Although a handful of reports from one
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Antimicrobial Susceptibility: Nationwide Patterns in the TRUST Surveillance Program
Ophthalmology Times
; Perspectives from specialists in ophthalmology, microbiology, and infectious disease Representing Ophthalmology Discussion Chair Marguerite B. McDonald, MD Clinical Professor of Ophthalmology Tulane University School of Medicine New Orleans, Louisiana Penny A. Asbell, MD Professor of Ophthalmology
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Trimethoprim displays greatest activity against methicillin-resistant Staphylococcus aureus
Ophthalmology Times
; Antimicrobial resistance Reviewed by Christopher Ta, MD Fort Lauderdale, FL - The newer fluoroquinolones have equal effectiveness against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptiblc S aureus (MSSA). With the exception of trimethoprim, a dihydrofolate reductase
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Nationwide Antimicrobial Surveillance in Ocular Isolates: Ocular TRUST: A New Tool for Ophthalmology
Ophthalmology Times
; Report from the Hawaiian Eye 2007 workshop A workshop at the 2007 Hawaiian Eye meeting featured the first results from the nationwide Ocular TRUST antimicrobial surveillance program. Highlights are presented in this supplement. Ocular TRUST: Nationwide In Vitro Antimicrobial Surveillance Ocular
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Newer quinolones able to tackle many ocular surface bacteria
Ophthalmology Times
; Topical antimicrobial agents In vitro susceptibility tests show next generation outperforms older ones against gram-positive isolates Stanford, CA-In vitro susceptibility test results demonstrate that the newer, 8-methoxy fluoroquinolones gatifloxacin (Zymar, Allergan) and moxifloxacin (Vigamox,
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Prevention and treatment of ocular infections: The role of new 4th generation fluoroquinolones
Ophthalmology Times
; ... S1-15. 19. The Charles T. Campbell Eye Microbiology Lab, University of Pittsburgh Medical Center. Unpublished data. 2001. 20. Tran TP, Le MT, Bui TH, Nguyen MT, Nguyen NX, Kuchle M. Posttraumatic endophthalmitis: risk-factors, microbiological diagnosis and ...
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Differentiating the Fourth-Generation Fluoroquinolones
Ophthalmology Times
; Published reports of experimental Laboratory investigations involving bacterial isolates from endophthalmitis1 and keratitis2 concur that both fourth-generation fluoroquinolones gatifloxacin and moxifloxacin are more potent than the second- and third-generation fluoroquinolones for gram-positive
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The Case for Fourth-generation Fluoroquinolones
Ophthalmology Times
; Fluoroquinolones have become the standard in ophthalmology for both the prevention and the management of bacterial infections. They are desirable because of their broad spectrum of antimicrobial activity. Fluoroquinolones provide coverage against both gram-positive and gram-negative bacteria
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Characterization of Streptococcus pneumoniae ophthalmic, systemic & commensal isolates by pulsed-field gel electrophoresis & ribotyping
Indian Journal of Medical Research
; Background & objectives: Streptococcus pneumoniae is common in ocular and systemic infections and is a part of normal nasopharyngeal flora. Very few studies regarding genetic analysis of S. pneumoniae isolates causing eye infections are available. This study was undertaken to do pulse field gel
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