Somatotropin regulates adipose tissue metabolism in neonatal swine

From: The Journal of Nutrition | Date: January 1, 1999| Author: | Copyright information

Somatotropin Regulates Adipose Tissue Metabolism in Neonatal Swine1'2'3

ABSTRACT Somatotropin (ST) reduces lipid deposition in growing and adult animals, but its effect in neonatal pigs is not clear. In this study, we tested the hypothesis that ST inhibits lipid deposition in neonatal pig adipose tissue. Four neonatal (2.9 0.1 kg, 7 d of age) and four growing (17.0 + 1.4 kg, 60 + 3 d of age) crossbred pigs were used. Subscapular adipose tissue fragments were cultured with or without ST (4.5 nmol/L) for 24 h in the absence or presence of insulin (7 nmol/L). After culture for 24 h with insulin ...

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