Letter to the editor: B-lymphoblastoid cell lines from cancer patients

From: In Vitro Cellular & Developmental Biology | Date: February 1, 1998| Author: | Copyright information

Dear Editor:

Epstein-Barr virus (EBV), a ubiquitous human herpesvirus, is the causative agent in infectious mononucleosis, a self-limiting lymphoproliferative disease in healthy individuals, and lymphoproliferative diseases in immune compromised patients. EBV is also strongly associated with a number of malignancies in humans including endemic African Burkitt's lymphoma, undifferentiated nasopharyngeal carcinoma, Hodgkin's disease, and peripheral T-cell lymphoma (for review see Purtilo et al., 1992). The clonality of infected EBVs in these tumor tissues strongly suggest that EBV might play a ...

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