Dosage of intrathecal pethidine and body weight

From: Anaesthesia and Intensive Care | Date: December 1, 1998| Author: | Copyright information

Dr Ngan Kee's recent review on intrathecal pethidine highlights an important point that in our opinion warrants further address'. As an allusion to that article, much of the meaningful surgical anaesthesia produced by intrathecal pethidine is due to its local anaesthetic effects on the central neuraxis.

Numerous studies on the behaviour of intrathecally administered local anaesthetic agents have failed to indicate either a positive or a linear relationship between their subarachnoid spread and the body weight of the patients. There is no reason to believe that intrathecal pethidine behaves ...

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