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Glutathone and glutathione ethyl ester supplementation of mice after glutathione homeostasis during exercise
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Glutathone and Glutathione Ethyl Ester Supplementation of Mice Alter Glutathione Homeostasis during Exercise12
Christiaan Leeuwenburgh3 and Li Li Ji4
Department of Kinesiology, Interdepartmental Graduate Program of Nutritional Sciences, University of Wisconsin-Madison, WI 53706
ABSTRACT The present study examined the effect of glutathione (GSH) and glutathione ethyl ester (GSH-E) supplementation on GSH homeostasis and exercise-induced oxidative stress. Male Swiss-Webster mice were randomly divided into 4 groups: starved for 24 h and injected with GSH or GSH-E (6 mmol/kg body wt, i.p.) 1 h ...
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Glutathione Metabolism and Its Implications for Health1
; ...Compelling evidence shows that GSH synthesis is regulated primarily by [gamma...about quantitative aspects of GSH synthesis and catabolism in the whole body...red^/thioredoxin^sub ox^ (4). GSH Synthesis. The synthesis of GSH from glutamate...
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Manipulation of glutathione and amino acid biosynthesis in the chloroplast
; ...chloroplast. We conclude that (a) GSH synthesis can occur in the chloroplast and...activity, (b) interactions between GSH synthesis and the pathways supplying the...chloroplastic up-regulation of GSH synthesis is associated with an activating...
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Distribution of Glutathione in Millstreams and Relationships to Chemical and Baking Properties of Flour
; ...650 kg/hr pilot roller mill. Glutathione (GSH) and oxidized glutathione (GSSG) were measured...Australian cultivars had higher levels of GSH and GSSG than the New Zealand cultivars...There was a strong correlation between GSH/GSSG and ash content in millstream flours...
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Maturation of Arabidopsis Seeds Is Dependent on Glutathione Biosynthesis within the Embryo1[C]
; Glutathione (GSH) has been implicated in maintaining the cell...during seed dehydration. To assess the role of GSH during development of Arabidopsis (Arabidopsis...mutants of GSH1, encoding the first enzyme of GSH biosynthesis, γ-glutamyl-cysteine synthetase...
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Global Ecology Corporation completes $4 million sale of GPS technology.(BUSINESS)
; ...GPS Technology to Global Safety Holdings (GSH). Under the financial terms of the sale, GEC will receive a minimum of $4 million over GSH's initial three or more years of operation...percent of current issued and outstanding) of GSH, which can be diluted only by a third-party...
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A Novel Family of Transporters Mediating the Transport of Glutathione Derivatives in Plants1
; ...compartmentation of reduced glutathione (GSH), oxidized glutathione (GSSG), and glutathione...cDNA restored growth on a medium containing GSH as the sole sulfur source. The strain expressing OsGT1 mediated [3H]GSH uptake, and this uptake was significantly...
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A [gamma]-Glutamyl Transpeptidase-Independent Pathway of Glutathione Catabolism to Glutamate via 5-Oxoproline in Arabidopsis1[W][OA]
; ...to the rate of GSH degradation (Leustek et al., 2000). GSH is synthesized from Glu, Cys, and Gly in a twostep, ATP-depende...Hell and Bergmann, 1990), and then Gly is incorporated by GSH synthetase (Wang and Oliver, 1996). The activity of γ-EC synthetase is regulated by GSH levels (Hell and ...
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Total Equivalent of Reactive Chemicals in 142 Human Food Items Is Highly Variable Within and Between Major Food Groups1
; ...human cancer or other diseases. Glutathione (GSH) reacts with and detoxifies electrophilic...chemicals in foods, we added a known amount of GSH to 142 commonly consumed food items and...reactive chemicals in terms of the amount of GSH lost during homogenization and extraction...
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Elevated glutathione biosynthetic capacity in the chloroplasts of transgenic tobacco plants paradoxically causes increased oxidative stress
; Glutathione (GSH), a major antioxidant in most aerobic organisms, is perceived...gamma-glutamylcysteine synthetase (gamma-ECS), foliar levels of GSH were raised threefold. Paradoxically, increased GSH biosynthetic capacity in the chloroplast resulted in greatly...
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Thiol/Disulfide Redox Status Is Oxidized in Plasma and Small Intestinal and Colonic Mucosa of Rats with Inadequate Sulfur Amino Acid Intake1
; ...similar tissue and plasma GSH/GSSG redox as rats that ate...for protein and glutathione (GSH) synthesis and for synthesis of taurine...and S-adenosylhomocysteine. GSH and sulfate function in detoxification...antioxidant function (2). GSH that is in the gut lumen is...For example, depletion ...
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