Biogenic amines and polyamines: Similar biochemistry for different physiological missions and biomedical applications

From: Critical Reviews in Biochemistry and Molecular Biology | Date: January 1, 2003| Author: | Copyright information

ABSTRACT: Biogenic amines are organic polycations derived from aromatic or cationic amino acids. All of them have one or more positive charges and a hydrophobic skeleton. Nature has evolved these molecules to play different physiological roles in mammals, but maintains similar patterns for their metabolic and intracellular handling. As deduced from this review, many questions still remain to be solved around their biochemistry and molecular biology, blocking our aims to control the relevant pathologies in which they are involved (cancer and immunological, neurological, and gastrointestinal ...

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