Elevated milk soluble CD14 in bovine mammary glands challenged with Escherichia coli lipopolysaccharide

From: Journal of Dairy Science | Date: July 1, 2003| Author: | Copyright information

ABSTRACT

The purpose of this study was to determine whether soluble CD 14 (sCD14) in milk was affected by stage of lactation, milk somatic cell count (SCC), presence of bacteria, or lipopolysaccharide (LPS)-induced inflammation. Milk samples from 100 lactating cows (396 functional quarters) were assayed for sCD14 in milk to determine effects of stage of lactation, SCC, and intramammary infection. The concentration of sCD14 was highest in transitional milk (0 to 4 d postpartum) and in milk with high SCC (> 750,000 cells/ml). Most of the infected quarters (> 80%) were infected by ...

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