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Apoptosis: Molecular mechanism for physiologic cell death
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Molecular biology is fast becoming the wave of the future in research as well as in the clinical laboratory. This trend toward determining cell function at this level is opening up doors to new techniques in evaluating and diagnosing such diseases as AIDS and cancer. This article focuses on apoptosis or programmed cell death, its morphological characteristics, its comparison to necrosis, its occurrence in development and homeostasis of multicellular organisms, its genetic regulation, and its involvement in diseases.
ABBREVIATIONS: AIDS = acquired immunodeficiency syndrome; DNA = ...
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DPL-1 DP, LIN-35 Rb and EFL-1 E2F Act With the MCD-1 Zinc-Finger Protein to Promote Programmed Cell Death in Caenorhabditis elegans
; ...9, ced-4, and ced-3 play major roles in programmed cell death in Caenorhabditis elegans. To identify genes...in transcriptional regulation to promote programmed cell death. PROGRAMMED cell death is important for many aspects of animal...
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A Genetic Screen Identifies New Regulators of Steroid-Triggered Programmed Cell Death in Drosophila
; ...of this steroid-triggered programmed cell death response. Pupal lethal mutants...death during development. PROGRAMMED cell death plays a central role in...additional level for controlling programmed cell death through inhibitor of apoptosis...
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Arabidopsis ACCELERATED CELL DEATH2 Modulates Programmed Cell Death[W]
; ...modulates the amount of programmed cell death (PCD) triggered by Pseudomonas...PCD-inducing events. INTRODUCTION Programmed cell death (PCD) is a common response...syringae also causes cell death (susceptible cell death), albeit at a slower rate...entirely ...
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MIT prof wins prize for probe of cell death.(News)
; ...honored for his pioneering work in the field of programmed cell death. Dr. Horvitz has made a discovery that is seminal...are not needed are eliminated. The concept of programmed cell death is illustrated in the case of webbed feet. Human...
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Programmed cell death in the apical ganglion during larval metamorphosis of the marine mollusc Ilyanassa obsoleta.
; ...disappear through a form of programmed cell death, rather than by incorporation...gene-activated process known as programmed cell death (PCD) (Kerr et al., 1972...example of non-apoptotic cell death occurs in the intersegmental...
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The science of cellular suicide. (research on cell death)
; ...and old ones die. Moreover, cell death can occur in predictable...is the actual mechanism of programmed cell death? Do cells simply wither away...are exploring mechanisms of cell death in the tobacco hawkmoth...the cells until just before cell death. To see ...
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Cucumber mosaic virus D satellite RNA-induced programmed cell death in tomato
; ...distinct spatial and temporal cell death pattern. The distinct features...fragmentation indicate that programmed cell death is involved. In addition...Pennell and Lamb, 1997). Programmed cell death (PCD) was first defined on...
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Programmed cell death in development and defense
; THE CONCEPT OF PROGRAMMED CELL DEATH (PCD) CAME FROM PLANTS Around the...number of physiologists studying cell death in various contexts for the rest...Plant physiologists knew that cell death is essential for normal development...
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MIT RESEARCHER OF CELL DEATH RECEIVES MARCH OF DIMES AWARD
; ...insights about genetics, cell death, communication between...influences on behavior. Programmed cell death, or apoptosis, allows...and flies, showing that programmed cell death is a fundamental property...birth defects may involve programmed cell ...
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The Arabidopsis BAP1 and BAP2 Genes Are General Inhibitors of Programmed Cell Death1[OA]
; ...Arabidopsis thaliana) as general inhibitors of programmed cell death (PCD) across the kingdoms. These two homologous...understanding the evolution of plant innate immunity. Programmed cell death (PCD) is a death program actively executed by...
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