Rapid polymerase chain reaction-based confirmation of cat scratch disease and Bartonella henselae infection

From: Archives of Pathology & Laboratory Medicine | Date: June 1, 2003| Author: | Copyright information

* Context.-Cat scratch disease (CSD) commonly occurs secondary to Bartonella henselae infection, and the diagnosis has traditionally been made by microscopic findings, the identification of organisms by cytochemistry, and clinical history. However, cytochemical analysis tends to be very difficult to interpret, and histology alone may be insufficient to establish a definitive diagnosis of CSD.

Objective.-To demonstrate the presence of B henselae in tissue suspected of involvement by CSD, using a novel polymerase chain reaction (PCR) assay.

Design.-Isolates of 8 henselae (American Tissue ...

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