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Ethylene rapidly up-regulates the activities of both monomeric GTP-binding proteins and protein kinase(s) in epicotyls of pea1
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It is demonstrated that, in etiolated pea (Pisum sativum) epicotyls, ethylene affects the activation of both monomeric GTP-binding proteins (monomeric G-proteins) and protein kinases. For monomeric G-proteins, the effect may be a rapid (2 min) and bimodal up-regulation, a transiently unimodal activation, or a transient down-regulation. Pretreatment with 1-methylcyclopropene abolishes the response to ethylene overall. Immunoprecipitation studies indicate that some of the monomeric G-proteins affected may be of the Rab class. Protein kinase activity is rapidly up-regulated by ethylene, the ...
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Biochemical Characterization of the Tobacco 42-kD Protein Kinase Activated by Osmotic Stress1[w]
; ...induces rapid activation of a 42-kD protein kinase, referred to as Nicoliana tabacum osmotic stress-activated protein kinase (NtOSAK). cDNA encoding the kinase...assigned to the SNFl-related protein kinase type 2 (SnRK2) family. The identity...
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Increased translocation of cardiac protein kinase C (beta)2 accompanies mild cardiac hypertrophy in rats fed saturated fat
; ...Increased Translocation of Cardiac Protein Kinase C 132 Accompanies Mild Cardiac Hypertrophy...ABSTRACT Signal transduction through protein kinase C (PKC) (beta)2 may modulate cardiac...Nutr. 133: 358-361, 2003. KEY WORDS: - protein kinase C - heart - dietary fat [Reference...
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A protein kinase is located in the micellar fraction of fresh pasteurized skimmed farm milk
; ABSTRACT Recombinant protein kinase CK2 from the yeast Schizosaccharomyces...better understand the action of protein kinase CK2 on milk proteins, we have...significant amount of intrinsic protein kinase activity was also found. The...
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Using Substrate-Binding Variants of the cAMP-Dependent Protein Kinase to Identify Novel Targets and a Kinase Domain Important for Substrate Interactions in Saccharomyces cerevisiae
; ...identification process for the cAMP-dependent protein kinase (PKA) in Saccharomyces cerevisiae...proteins. The net effect of activating any protein kinase therefore is due to the collective...of that kinase. The cAMP-dependent protein kinase (PKA) is one of the best-characterized...
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Sphingosine-1-phosphate inhibition of apoptosis requires mitogen-activated protein kinase phosphatase-1 in mouse fibroblast C3H10T = cells1
; ...ERK) activation and mitogen-activated protein kinase phosphatase-1 (MKP-1) were examined...S1P (ceramine/S1P). Stress activated protein kinase or c-Jun N-terminal kinase (SAPK/JNK...as shown using the mitogen-activated protein kinase kinase inhibitor, PD98059. Transfection...
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Overexpression of p34cdc2 protein kinase in epithelial ovarian carcinoma
; ...role of expression of p34^sup cdc2^ protein kinase in normal, benign, and malignant ovarian...monoclonal antibody to human p34^sup cdc2^ protein kinase, followed by detection with use of...cystadenomas failed to stain for p34^sup cdc2^ protein kinase. Of the 24 EOC specimens, ...
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Researchers are getting specific about protein kinase inhibitora
; ...overrated In signal transduction research, protein kinase inhibitors help scientists tease out...Cohen recalls, "it turned out to be a protein kinase that we'd just discovered ourselves...others, convinced Cohen to focus on protein kinase inhibitors. "From my standpoint, these...
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In Vivo Activation of Protein Kinase A in Schizosaccharomyces pombe Requires Threonine Phosphorylation at Its Activation Loop and Is Dependent on PDK1
; ABSTRACT Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in cellular signaling...the AGC family of kinases. This family includes protein kinase C (PKC), protein kinase B (PKB), p70/p90 ribosomal S6 kinases (RSK and...
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Activation of a Novel Transcription Factor through Phosphorylation by WIPK, a Wound-Induced Mitogen-Activated Protein Kinase in Tobacco Plants1
; Wound-induced protein kinase (WIPK) is a tobacco (Nicotiana tabacum) mitogen-activated protein kinase known to play an essential role in defense...three-tier kinases, mitogen-activated protein kinase (MAPK) extra cellular signal-regulated...
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Multicolor imaging of CA(2+) and protein kinase C signals using novel epifluorescence microscopy
; ...sup 2+^-CaM) and phosphorylation by protein kinase C (PKC). The two signals compete for...1993. The MARCKS family of cellular protein kinase C substrates. J. Biol. Chem. 268:1501-15...F. Whitfield. 1995a. Stimulation of protein kinase C during Caz+-induced keratinocyte...
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